| Date | Time* | Comp |
| Home | Score | Away |
|
| Opposition | Result | Venue | TV/Attendance |
|
|---|
| December 2021 |
| Sat 11 Dec | 15:15 | ERCHAMPC-PA |  | Leinster Rugby | 45 - 20 | Bath Rugby |  | H |
| W 45-20 | Aviva Stadium | 25,403 | More |
| Sat 11 Dec | 18:30 | ERCHAMPC-PA |  | ASM Clermont Auvergne | 23 - 29 | Ulster Rugby |  | A |
| W 29-23 | Stade Marcel Michelin | 14,443 | More |
| Sun 12 Dec | 13:00 | ERCHAMPC-PB |  | Connacht Rugby | 36 - 9 | Stade Francais Paris |  | H |
| W 36-9 | Sportsground | 5,277 | More |
| Sun 12 Dec | 15:15 | ERCHAMPC-PB |  | Wasps | 14 - 35 | Munster Rugby |  | A |
| W 35-14 | Coventry Building Society Arena | 6,716 | More |
| Fri 17 Dec | 20:00 | ERCHAMPC-PA | | Ulster Rugby | 27 - 22 | Northampton Saints |  | H |
| W 27-22 | Kingspan Stadium | 14,712 | More |
| Fri 17 Dec | 21:00 | ERCHAMPC-PA |  | Montpellier | 28 - 0 | Leinster Rugby | | A |
| L 0-28 | TBA |
| More |
| Sat 18 Dec | 20:00 | ERCHAMPC-PB | | Munster Rugby | 19 - 13 | Castres Olympique |  | H |
| W 19-13 | Thomond Park | 21,250 | More |
| Sun 19 Dec | 13:00 | ERCHAMPC-PB |  | Leicester Tigers | 29 - 23 | Connacht Rugby | | A |
| L 23-29 | Mattioli Woods Welford Road Stadium | 17,222 | More |
| January 2022 |
| Fri 14 Jan | 21:00 | ERCHAMPC-PB | | Castres Olympique | 13 - 16 | Munster Rugby | | A |
| W 16-13 | Pierre-Fabre (Pierre-Antoine) | 5,000 | More |
| Sat 15 Jan | 15:15 | ERCHAMPC-PB | | Connacht Rugby | 28 - 29 | Leicester Tigers | | H |
| L 28-29 | Sportsground | 3,064 | More |
| Sun 16 Jan | 13:00 | ERCHAMPC-PA | | Leinster Rugby | 89 - 7 | Montpellier | | H |
| W 89-7 | RDS Arena | 5,000 | More |
| Sun 16 Jan | 15:15 | ERCHAMPC-PA | | Northampton Saints | 20 - 24 | Ulster Rugby | | A |
| W 24-20 | cinch Stadium at Franklin's Gardens | 13,271 | More |
| Sat 22 Jan | 13:00 | ERCHAMPC-PA | | Bath Rugby | 7 - 64 | Leinster Rugby | | A |
| W 64-7 | Recreation Ground | 13,761 | More |
| Sat 22 Jan | 17:30 | ERCHAMPC-PA | | Ulster Rugby | 34 - 31 | ASM Clermont Auvergne | | H |
| W 34-31 | Kingspan Stadium | 14,928 | More |
| Sun 23 Jan | 14:00 | ERCHAMPC-PB | | Stade Francais Paris | 37 - 31 | Connacht Rugby | | A |
| L 31-37 | Stade Jean Bouin | 5,000 | More |
| Sun 23 Jan | 15:15 | ERCHAMPC-PB | | Munster Rugby | 45 - 7 | Wasps | | H |
| W 45-7 | Thomond Park | 13,000 | More |
| April 2022 |
| Fri 8 Apr | 20:00 | ERCHAMPC-R16-1 | | Connacht Rugby | 21 - 26 | Leinster Rugby | | H |
| L 21-26 | Sportsground | 8,129 | More |
| Sat 9 Apr | 16:15 | ERCHAMPC-R16-1 |  | Toulouse | 20 - 26 | Ulster Rugby | | A |
| W 26-20 | Stade Toulouse | 27,760 | More |
| Sat 9 Apr | 17:30 | ERCHAMPC-R16-1 |  | Exeter Chiefs | 13 - 8 | Munster Rugby | | A |
| L 8-13 | Sandy Park | 10,307 | More |
| Fri 15 Apr | 17:30 | ERCHAMPC-R16-1 | | Leinster Rugby | 56 - 20 | Connacht Rugby | | H |
| W 56-20 | Aviva Stadium | 32,604 | More |
| Sat 16 Apr | 15:00 | ERCHAMPC-R16-1 | | Munster Rugby | 26 - 10 | Exeter Chiefs | | H |
| W 26-10 | Thomond Park | 21,133 | More |
| Sat 16 Apr | 20:00 | ERCHAMPC-R16-1 | | Ulster Rugby | 23 - 30 | Toulouse | | H |
| L 23-30 | Kingspan Stadium | 16,866 | More |
| May 2022 |
| Sat 7 May | 15:00 | ERCHAMPC-QF | | Munster Rugby | 24 - 24 | Toulouse | | H |
| D 24-24 | Aviva Stadium | 40,476 | More |
| Sat 7 May | 17:30 | ERCHAMPC-QF | | Leicester Tigers | 14 - 23 | Leinster Rugby | | A |
| W 23-14 | Mattioli Woods Welford Road Stadium | 19,066 | More |
| Sat 14 May | 15:00 | ERCHAMPC-SF | | Leinster Rugby | 40 - 17 | Toulouse | | H |
| W 40-17 | Aviva Stadium | 42,076 | More |
| Sat 28 May | 17:45 | ERCHAMPC-F | | Leinster Rugby | v | La Rochelle |  | H |
|
| Stade Velodrome |
| More |
|
